If you do not follow directions and use more than one pump it can be irritating. Also make sure skin is bone dry before applying. Retinol tends to travel. So while you won't be using it near say your eyebrows if you get waxed tell you water as it tends to travel and can really hurt and peel skin if you wax.

My derm recommend this and hands down the best retinol I have ever used. It actually purged my skin and after I got through the Retinol uglies I wad left with absolutely smooth, glowing skin. I have never had a retinol act like this before. It's worth every penny.

SkinMedica - Azureblu review for Retinol Complex 0.5

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